An early and targeted preparation for the university study is a fundamental prerequisite of future success. Paper offers an overview of activities of the Support Centre for Visually Impaired Students focused on early preparation of students with VI for studying sciences at university and forms of special support for students and academic staff during the study. As a result of a TEMPUS project the “Support Centre without barriers” at Moldova State University was created. The state of the art of study opportunities at MSU, mission of the centre and plans for an internatinal co-operation will be presented.